Rat VEGF ELISA Kit Distributor

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Standard - EK383.jpg

Brand	MultiSciences
CatNum	70-EK383
Product Name	Rat VEGF ELISA Kit
Customs Name	Rat VEGF ELISA Kit
Application	ELISA
Reactivity	Rat
Assay Type	Sandwich ELISA
Suitable Sample Type	serum, plasma, cell culture supernates
Format	96-well strip plate
Storage	4? (unopened) standard stored at -20?, others stored at 4? (opened)
Shipping Condition	4?
Sample Volume	20 µl
Sensitivity	2.41 pg/ml
Standard Curve Range	39.06 - 2500 pg/ml
Spike Recovery Range	87 % - 106 %
Mean Spike Recovery	0.98
CV of Intra plate	4.4 % - 6.3 %
CV of Inter plate	4.5 % - 6.0 %
Release Date	2015/8/29
Components	96-well polystyrene microplate coated with a monoclonal antibody against VEGF Rat VEGF Standard, lyophilized VEGF Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers
Describtion	This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of rat VEGF. The Rat VEGF ELISA is for research use only. Not for diagnostic or therapeutic procedures. Vascular endothelial growth factor (VEGF) is a sub - family of growth factors, to be specific, the platelet - derived growth factor family of cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the denovoformation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature). VEGF is a signal protein produced by cells that imulates vasculogenesis and angiogenesis. It is part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. VEGF is best known for its role in vasculogenesis. During embryogenesis, VEGF regulates the proliferation, migration, and survival of endothelial cells, thus regulating blood vessel density and size, but playing no role in determining vascular patterns. Serum concentration of VEGF is high in bronchial asthma and diabetes mellitus. When VEGF is overexpressed, it can contribute to disease. Solid cancers cannot grow beyond a limited size without an adequate blood supply; cancers that can express VEGF are able to grow and metastasize. Overexpression of VEGF can cause vascular disease in the retina of the eye and other parts of the body. Drugs such as bevacizumab and Ranibizumab can inhibit VEGF and control or slow those diseases.

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