Principle Of Spray Drying Granulation In Pharmaceutical Industry

The powder granule in the container (fluization) appear in the state of fluidization. It is preheated and mixed with chen and heated air. At the same time the solution of adhesive solvent is fogged and sprayed into the container. It makes some particles become granulating that contains adhesive. Being of unceasing dry through hot air, the moisture in the granulation is evaporated and the adhesive is solidification. The process is carried out continuously. Finally it forms ideal, uniform and porous granules.

The machine is composed of machine, air handing system, heating system, exhaust and dust filter system etc. When it works, the material enter the bin of the fluid bed granulator. Set the procedures and parameters according to process of requirements and the machine will start working. After filtered by the air handling system and heated by the heating system, the air enters the main machine. After the materials are fluidized by hot air, the moisture is evaporated rapidly and the materials are dried instantly. After the operations are completed according to the set procedures and parameters, the material silo is pushed out and assembled onto the lifting and turning granule sizing machine for lifting discharging, so as to effectively control dust pollution and cross contamination.