MK-677 CAS No 159752-10-0

  • Description
Product Detail

Bodybuilding Drug MK-677/Ibutamoren Mesylate/Nutrobal Steroid Sarm Powder 159752-10-0 for Muscle Growth

Structure


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Product Details

Product Name

MK-677

Chemical Name

Ibutamoren,MK-0677; nutrobal; L 163,191; Ibutamoren mesylate; Crescendo

CAS Number

159752-10-0

EINECS Number

212-729-3

Molecular Formula

C27H36N4O5S.CH4O3S

Molecular Weight

624.776

Molecular Structure


Assay

99.5%

Appearance

White powder

 

Description  
 MK-677 is an oral SECRETAGOGUE that provides higher amplitude to the dozen or more pulses put out by the pituitary gland over the 25 hour half-life of the drug. Once daily use before bed at a dose of 25mg provides all of the benefits of elevated Igf1 such as deeper sleep with more vivid dreams, improved skin, faster hair and nail growth, fat loss, lean muscle gain, increased strength, greater nitrogen retention the the skeletal muscles, greater protein synthesis, etc.
 
COA

TEST

ACCEPTANCE CRITERLA

RESULTS

TLC

Positive

Identification

UV spectrum

Positive

IR spectrum

Positive

Characteristics

White to yellowish-white crystalline powder

conform

Melting point

32 ~ 37ºC

33~36ºC

Specific optical rotation

+77°~+82°

+79.3°

Loss on drying

=0.5%

0.15%

Assay

97 ~ 103%

99.08%

Free heptanoic acid

=0.2 %

0.10%

Related substances

=2%

Pass

Acetone =100ppm

Pass

Residual solvents(GC)

Methanol =100ppm

Pass

Pyridine =100ppm

Pass


 Usage  
 MK-677 is a medicine which acts as a potent, orally active growth hormones secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin.
 It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormones and IGF-1, but without affecting cortisol levels.
 It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormones deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density,
making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.

How Ibutamoren (MK-677) WORKS?

Growth hormone pulse intensity can be increased through 4 possible mechanisms:
 ? Increasing GHRH (growth hormone releasing hormone) release.
 ? Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.
 ? Reducing somatostatin release (somatostatin turns off GH release).
 ? Inhibiting of somatostatin receptor signaling.
 ? Ibutamoren (MK-677) was found to work through all four of these mechanisms. After ingestion, Growth Hormone (GH) was shown to increase dose dependently, at doses starting at 5 milligrams (mgs) a day
 
 Benefits  
 1. Reversal of Nitrogen Wasting
 MK-677 can stop the nitrogen wasting effect of a caloric deficit on the body. This means that as you limit your calories and exercise more to lose weight, your body won't resort to breaking down your muscles for energy.
 In study participants, MK-677 helped them to maintain muscle mass and instead use their fat stores as energy.
 2. Less Fat Stored
 Supplementing with MK-677 can influence where your body stores the calories you eat. In most people, when we eat more calories than we burn in a day some of those calories will be stored as fat.
 MK-677 changes that, and instead your body deposits those calories into the muscles, resulting in muscle growth.
 3. Increased Bone Mineral Density
 Older adults who were given MK-677 as part of a clinical study saw increases in bone density and strength.
 This means that the supplement can decrease the risk of developing degenerative bone diseases like osteoporosis and help to maintain bone health in older adults.

 

Our Advantages:

 1)Great quality, purity and favourable.
 Our company is a professional production of hormone intermediates for many years, our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, you can trust us.
 And we are the manufactory, so no problem for us to control the quality. 
 2)Payment way
 Payment term: western union, money gram,bank transfer and paypal
 We can accept paypal, then it can guarantee you can get your goods without any custom problem     
 3)Reshipping Policy
 We also do reship service with free cost if goods were cached by custom     
 4)Fast &Secure Shipping
 Generally,you will receive the product within 10-20 working days.
 The rate of passing customs is more than 90%. 

 

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