Mebendazole

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Description

Product Detail

1. CAS No :31431-39-7

2. EINECS No :250-635-4

3. Model Number :9801

4. Other Names :MBZ

5. Color: white

6. Purity: 98%-105%

Items	Specification	results
Characteristic	A white or almost white powder	Almost white powder
Solubility	Practically insoluble in water,in alcohol and in methylene chloride,It shows polymorphism	conforms
Infrared Absorption	Comform to the spectrum obtained from Mebendazole RS.	conforms
Related substances	Impurity G not more than 0.5% Any other individual impurity not more than 0.25% Total impurities not more than 1.0%	<0.05% <0.05% <0.05%
Loss on drying	Not more than 0.5%	0.06%
Residue on ignition	Not more than 0.1%	0.06%
Partical size distribution	Particals smaller than 20um should be no less than 90%	conforms
Assay	It contains not less than 99.0% and not more than 101.0% of C16H13N3O3 calculated on the dried basis	99.8%
Conclusion	The quality of the above commodity complies with the standard of BP2008 and in-house specification.

Mebendazole or MBZ is a benzimidazole drug. It is used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms

Mebendazole is thought to work by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells: thereby blocking the uptake of glucose and other nutrients, resulting in the gradual immobilization and eventual death of the helminths. The drug is a highly effective broad spectrum antihelminitic indicated for the treatment of nematode infestations, including round worm, whip worm, thread worm, and hook worm. It is poorly absorbed and has no systemic effects.

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