GDF-8 CAS No.: 232-895-0
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1
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Pieces
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Origin
China Mainland
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Product Detail
Pure Myostatin HMP Peptide 1mg 99% Bodybuilding Human Growth Hormone Peptide GDF-8 1mg for Muscle Growth GDF-8 Injectable Lyophilized Powder For Bodybuilding Pharmaceutical Peptide Myostatin Peptide Gdf-8/Myostatin 1mg/Vial for Sale
Products Specifications:
99% GDF-8 powder
Quick Details
Product name: GDF-8 (Growth Differentiation Factor 8)
Purity: >98%
Specification: 1mg
Storage:2-8 degree centigrade refrigerator
Package: 10 Vials/Kit
Deliver:1 working day for ready goods,7 days to your destination.
Pacakge:1kit=10vials Alumnium foil+bubble+carton
Customized:accepted.
Country of Origin: China
Description
Myostatin (also known as growth factor 8, abbreviated as GDF-8) is a protein that is produced and released by muscle cells that act on myoblast autocrine function to inhibit myogenesis: muscle cell growth and Differentiation. In humans, it is encoded by the MSTN gene. Myosin is a secreted growth factor that is a member of the TGF beta family of proteins.
Animals lacking myostatin or substances treated with substances that block myostatin activity have significantly more muscle mass. In addition, individuals with mutations in the two copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have a therapeutic effect in the treatment of muscle wasting diseases such as muscular dystrophy.
Application:
The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These myostatin "knockout" mice have approximately twice as much muscle as normal mice. These mice were subsequently named "mighty mice".
Naturally occurring deficiencies of myostatin have been identified in cattle by Ravi Kambadur, whippets, and humans; in each case the result is a dramatic increase in muscle mass. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206. This is likely to cause the muscular phenotype of this breed of sheep.
GDF 8 / Myostatin Structure and mechanism of action
Human myosin is composed of two identical subunits, each consisting of 109 amino acid residues (NCBI database claims that human myostatin up to 375 residues). The total molecular weight is 25.0 kDa. The protein is inactive until the protease cleaves the NH 2 terminal or "predomain" portion of the molecule, resulting in an active COOH terminal dimer.
Myostatin also inhibits Akt, a kinase that is sufficient to cause muscle hypertrophy, partly through the activation of protein synthesis. However, Akt is not responsible for all observed muscular dystrophy effects mediated by myostatin inhibition. Muscle somatostatin therefore acts in two ways: by inhibiting muscle differentiation and inhibiting Akt-induced protein synthesis.
Myostatin
Myosin (also known as growth differentiation, f8, abbreviated as GDF-8) is a protein that produces and releases muscle cells, which act on myoblast autocrine function to inhibit muscle cell formation: muscle cell growth and differentiation The In humans, it is encoded by the MSTN gene. Myosin is a secreted growth factor that is a member of the TGF beta family of proteins.
Animals lacking myostatin or substances treated with substances that block myostatin activity have significantly more muscle mass. In addition, individuals with mutations in the two copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have a therapeutic effect in the treatment of muscle wasting diseases such as muscular dystrophy.
Peptides series
Polypeptide Hormones | Specification | |
CJC1295 without DAC | CAS 863288-34-0 | 2mg/vial |
CJC1296 with DAC | CAS 863288-34-0 | 2mg/vial |
Hexarelin | CAS 140703-51-1 | 2mg/vial |
MGF | 2mg/vial | |
PEG MGF | 2mg/vial | |
MT-1 | CAS 75921-69-6 | 10mg/vial |
MT-2 | CAS 121062-08-6 | 10mg/vial |
GHRP-2 | CAS 158861-67-7 | 5mg/vial |
10mg/vial | ||
GHRP-6 | CAS 87616-84-0 | 5mg/vial |
10mg/vial | ||
Ipamorelin | CAS 170851-70-4 | 2mg/vial |
Sermorelin | CAS 86168-78-7 | 2mg/vial |
Oxytocin | CAS 50-56-6 | 2mg/vial |
TB500 | CAS 77591-33-4 | 2mg/vial |
Pentadecapeptide BPC 157 | 2mg/vial | |
AOD 9604 | CAS 221231-10-3 | 2mg/vial |
Triptorelin | CAS 57773-63-4 | 2mg/vial |
Tesamorelin | CAS 218949-48-5 | 2mg/vial |
DSIP | CAS 62568-57-4 | 2mg/vial |
Selank | 5mg/vial | |
PT141 | CAS 189691-06-3 | 10mg/vial |
Gonadorelin | CAS 34973-08-5 | 2mg/vial |
Epitalon | 307297-39-8 | 10mg/vial |
Follistatin 344 | 1mg/vial | |
IGF-1 LR3 | 1mg/vail | |
ACE 031 | 1mg/vail | |
GDF-8 | 1mg/vail |
FAQ
Q1:Have your product quality been approved by Third Party Lab?
A:Yes,All products are strictly tested by our QC,confirmed by QA and approved by third party lab in China,USA,Canada,Germany,UK,Italy,France etc.So you will be assured with Good Quality if you choose us.
Q2:How do you treat quality complaint?
A:First of all,our QC department will do strict examination of our export products by HPLC,UV,GC,TLC and so on in order to reduce the quality problem to near zero.If there is a real quality problem,caused by us,we will send you free goods for replacement or refund your loss.
Q3:Do you accept sample order?
A:Yes,we accept small order from 10g,100g and 1kg for your evaluation quality of our goods.
Q4:Is there any discount?
A:Yes,for larger quantity,we always support with better price.
Q5:How long does it take to arrive?
A:It is Depending on your location,
For small order,please expect 5-7 days by DHL,UPS,TNT,FEDEX,EMS.
For mass order,please allow 5-8 days by Air,20-35 days by Sea.
Q6:Do you have any reshipment policy?
Yes we will reship for totally free if your parcles is seizd by customs unlucky,you dont need to pay any more money
Q7:what payment do you offer?
TT(bank transfer),west union,money gram,paypal
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